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Hematology and Clinical Chemistry Reference Ranges for Laboratory-Bred Natal Multimammate Mice (Mastomys natalensis)

Laboratory-controlled physiological data for the multimammate rat (Mastomys natalensis) are scarce, despite this species being a known reservoir and vector for zoonotic viruses, including the highly pathogenic Lassa virus, as well as other arenaviruses and many species of bacteria. For this reason,...

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Autores principales: Wozniak, David M., Kirchoff, Norman, Hansen-Kant, Katharina, Sogoba, Nafomon, Safronetz, David, Prescott, Joseph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7910822/
https://www.ncbi.nlm.nih.gov/pubmed/33513733
http://dx.doi.org/10.3390/v13020187
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author Wozniak, David M.
Kirchoff, Norman
Hansen-Kant, Katharina
Sogoba, Nafomon
Safronetz, David
Prescott, Joseph
author_facet Wozniak, David M.
Kirchoff, Norman
Hansen-Kant, Katharina
Sogoba, Nafomon
Safronetz, David
Prescott, Joseph
author_sort Wozniak, David M.
collection PubMed
description Laboratory-controlled physiological data for the multimammate rat (Mastomys natalensis) are scarce, despite this species being a known reservoir and vector for zoonotic viruses, including the highly pathogenic Lassa virus, as well as other arenaviruses and many species of bacteria. For this reason, M. natalensis is an important rodent for the study of host-virus interactions within laboratory settings. Herein, we provide basic blood parameters for age- and sex-distributed animals in regards to blood counts, cell phenotypes and serum chemistry of a specific-pathogen-monitored M. natalensis breeding colony, to facilitate scientific insight into this important and widespread rodent species.
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spelling pubmed-79108222021-02-28 Hematology and Clinical Chemistry Reference Ranges for Laboratory-Bred Natal Multimammate Mice (Mastomys natalensis) Wozniak, David M. Kirchoff, Norman Hansen-Kant, Katharina Sogoba, Nafomon Safronetz, David Prescott, Joseph Viruses Article Laboratory-controlled physiological data for the multimammate rat (Mastomys natalensis) are scarce, despite this species being a known reservoir and vector for zoonotic viruses, including the highly pathogenic Lassa virus, as well as other arenaviruses and many species of bacteria. For this reason, M. natalensis is an important rodent for the study of host-virus interactions within laboratory settings. Herein, we provide basic blood parameters for age- and sex-distributed animals in regards to blood counts, cell phenotypes and serum chemistry of a specific-pathogen-monitored M. natalensis breeding colony, to facilitate scientific insight into this important and widespread rodent species. MDPI 2021-01-27 /pmc/articles/PMC7910822/ /pubmed/33513733 http://dx.doi.org/10.3390/v13020187 Text en © 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Wozniak, David M.
Kirchoff, Norman
Hansen-Kant, Katharina
Sogoba, Nafomon
Safronetz, David
Prescott, Joseph
Hematology and Clinical Chemistry Reference Ranges for Laboratory-Bred Natal Multimammate Mice (Mastomys natalensis)
title Hematology and Clinical Chemistry Reference Ranges for Laboratory-Bred Natal Multimammate Mice (Mastomys natalensis)
title_full Hematology and Clinical Chemistry Reference Ranges for Laboratory-Bred Natal Multimammate Mice (Mastomys natalensis)
title_fullStr Hematology and Clinical Chemistry Reference Ranges for Laboratory-Bred Natal Multimammate Mice (Mastomys natalensis)
title_full_unstemmed Hematology and Clinical Chemistry Reference Ranges for Laboratory-Bred Natal Multimammate Mice (Mastomys natalensis)
title_short Hematology and Clinical Chemistry Reference Ranges for Laboratory-Bred Natal Multimammate Mice (Mastomys natalensis)
title_sort hematology and clinical chemistry reference ranges for laboratory-bred natal multimammate mice (mastomys natalensis)
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7910822/
https://www.ncbi.nlm.nih.gov/pubmed/33513733
http://dx.doi.org/10.3390/v13020187
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