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Hematology and Clinical Chemistry Reference Ranges for Laboratory-Bred Natal Multimammate Mice (Mastomys natalensis)
Laboratory-controlled physiological data for the multimammate rat (Mastomys natalensis) are scarce, despite this species being a known reservoir and vector for zoonotic viruses, including the highly pathogenic Lassa virus, as well as other arenaviruses and many species of bacteria. For this reason,...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7910822/ https://www.ncbi.nlm.nih.gov/pubmed/33513733 http://dx.doi.org/10.3390/v13020187 |
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author | Wozniak, David M. Kirchoff, Norman Hansen-Kant, Katharina Sogoba, Nafomon Safronetz, David Prescott, Joseph |
author_facet | Wozniak, David M. Kirchoff, Norman Hansen-Kant, Katharina Sogoba, Nafomon Safronetz, David Prescott, Joseph |
author_sort | Wozniak, David M. |
collection | PubMed |
description | Laboratory-controlled physiological data for the multimammate rat (Mastomys natalensis) are scarce, despite this species being a known reservoir and vector for zoonotic viruses, including the highly pathogenic Lassa virus, as well as other arenaviruses and many species of bacteria. For this reason, M. natalensis is an important rodent for the study of host-virus interactions within laboratory settings. Herein, we provide basic blood parameters for age- and sex-distributed animals in regards to blood counts, cell phenotypes and serum chemistry of a specific-pathogen-monitored M. natalensis breeding colony, to facilitate scientific insight into this important and widespread rodent species. |
format | Online Article Text |
id | pubmed-7910822 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-79108222021-02-28 Hematology and Clinical Chemistry Reference Ranges for Laboratory-Bred Natal Multimammate Mice (Mastomys natalensis) Wozniak, David M. Kirchoff, Norman Hansen-Kant, Katharina Sogoba, Nafomon Safronetz, David Prescott, Joseph Viruses Article Laboratory-controlled physiological data for the multimammate rat (Mastomys natalensis) are scarce, despite this species being a known reservoir and vector for zoonotic viruses, including the highly pathogenic Lassa virus, as well as other arenaviruses and many species of bacteria. For this reason, M. natalensis is an important rodent for the study of host-virus interactions within laboratory settings. Herein, we provide basic blood parameters for age- and sex-distributed animals in regards to blood counts, cell phenotypes and serum chemistry of a specific-pathogen-monitored M. natalensis breeding colony, to facilitate scientific insight into this important and widespread rodent species. MDPI 2021-01-27 /pmc/articles/PMC7910822/ /pubmed/33513733 http://dx.doi.org/10.3390/v13020187 Text en © 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Wozniak, David M. Kirchoff, Norman Hansen-Kant, Katharina Sogoba, Nafomon Safronetz, David Prescott, Joseph Hematology and Clinical Chemistry Reference Ranges for Laboratory-Bred Natal Multimammate Mice (Mastomys natalensis) |
title | Hematology and Clinical Chemistry Reference Ranges for Laboratory-Bred Natal Multimammate Mice (Mastomys natalensis) |
title_full | Hematology and Clinical Chemistry Reference Ranges for Laboratory-Bred Natal Multimammate Mice (Mastomys natalensis) |
title_fullStr | Hematology and Clinical Chemistry Reference Ranges for Laboratory-Bred Natal Multimammate Mice (Mastomys natalensis) |
title_full_unstemmed | Hematology and Clinical Chemistry Reference Ranges for Laboratory-Bred Natal Multimammate Mice (Mastomys natalensis) |
title_short | Hematology and Clinical Chemistry Reference Ranges for Laboratory-Bred Natal Multimammate Mice (Mastomys natalensis) |
title_sort | hematology and clinical chemistry reference ranges for laboratory-bred natal multimammate mice (mastomys natalensis) |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7910822/ https://www.ncbi.nlm.nih.gov/pubmed/33513733 http://dx.doi.org/10.3390/v13020187 |
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