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Phytonutrient and Nutraceutical Action against COVID-19: Current Review of Characteristics and Benefits
The trend toward using phytonutrients and/or nutraceuticals (P/Ns) with the aim of impacting immune health has increased in recent years. The main reason is that properties of P/Ns are associated with possible immunomodulating effects in the prevention and complementary treatment of viral diseases,...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7910826/ https://www.ncbi.nlm.nih.gov/pubmed/33573173 http://dx.doi.org/10.3390/nu13020464 |
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author | Pastor, Nitida Collado, Maria Carmen Manzoni, Paolo |
author_facet | Pastor, Nitida Collado, Maria Carmen Manzoni, Paolo |
author_sort | Pastor, Nitida |
collection | PubMed |
description | The trend toward using phytonutrients and/or nutraceuticals (P/Ns) with the aim of impacting immune health has increased in recent years. The main reason is that properties of P/Ns are associated with possible immunomodulating effects in the prevention and complementary treatment of viral diseases, including COVID-19 and other respiratory infections. In the present review, we assess the scientific plausibility of specific P/Ns for this purpose of preventative and therapeutic interventions against COVID-19, with an emphasis on safety, validity, and evidence of efficacy against other viruses. Five potential candidates have been identified after reviewing available studies (in silico, in vitro, and in vivo) in which certain flavonoids have demonstrated a potential for use as adjuvant therapeutic agents against viral infections, including COVID-19. As these are often better tolerated than pharmacological treatments, their use could be more widely considered if additional detailed studies can validate the existing evidence. |
format | Online Article Text |
id | pubmed-7910826 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-79108262021-02-28 Phytonutrient and Nutraceutical Action against COVID-19: Current Review of Characteristics and Benefits Pastor, Nitida Collado, Maria Carmen Manzoni, Paolo Nutrients Review The trend toward using phytonutrients and/or nutraceuticals (P/Ns) with the aim of impacting immune health has increased in recent years. The main reason is that properties of P/Ns are associated with possible immunomodulating effects in the prevention and complementary treatment of viral diseases, including COVID-19 and other respiratory infections. In the present review, we assess the scientific plausibility of specific P/Ns for this purpose of preventative and therapeutic interventions against COVID-19, with an emphasis on safety, validity, and evidence of efficacy against other viruses. Five potential candidates have been identified after reviewing available studies (in silico, in vitro, and in vivo) in which certain flavonoids have demonstrated a potential for use as adjuvant therapeutic agents against viral infections, including COVID-19. As these are often better tolerated than pharmacological treatments, their use could be more widely considered if additional detailed studies can validate the existing evidence. MDPI 2021-01-30 /pmc/articles/PMC7910826/ /pubmed/33573173 http://dx.doi.org/10.3390/nu13020464 Text en © 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Pastor, Nitida Collado, Maria Carmen Manzoni, Paolo Phytonutrient and Nutraceutical Action against COVID-19: Current Review of Characteristics and Benefits |
title | Phytonutrient and Nutraceutical Action against COVID-19: Current Review of Characteristics and Benefits |
title_full | Phytonutrient and Nutraceutical Action against COVID-19: Current Review of Characteristics and Benefits |
title_fullStr | Phytonutrient and Nutraceutical Action against COVID-19: Current Review of Characteristics and Benefits |
title_full_unstemmed | Phytonutrient and Nutraceutical Action against COVID-19: Current Review of Characteristics and Benefits |
title_short | Phytonutrient and Nutraceutical Action against COVID-19: Current Review of Characteristics and Benefits |
title_sort | phytonutrient and nutraceutical action against covid-19: current review of characteristics and benefits |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7910826/ https://www.ncbi.nlm.nih.gov/pubmed/33573173 http://dx.doi.org/10.3390/nu13020464 |
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