Transcriptome Analysis Reveals Altered Inflammatory Pathway in an Inducible Glial Cell Model of Myotonic Dystrophy Type 1

Myotonic dystrophy type 1 (DM1), the most frequent inherited muscular dystrophy in adults, is caused by the CTG repeat expansion in the 3′UTR of the DMPK gene. Mutant DMPK RNA accumulates in nuclear foci altering diverse cellular functions including alternative splicing regulation. DM1 is a multisys...

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Detalles Bibliográficos
Autores principales: Azotla-Vilchis, Cuauhtli N., Sanchez-Celis, Daniel, Agonizantes-Juárez, Luis E., Suárez-Sánchez, Rocío, Hernández-Hernández, J. Manuel, Peña, Jorge, Vázquez-Santillán, Karla, Leyva-García, Norberto, Ortega, Arturo, Maldonado, Vilma, Rangel, Claudia, Magaña, Jonathan J., Cisneros, Bulmaro, Hernández-Hernández, Oscar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7910866/
https://www.ncbi.nlm.nih.gov/pubmed/33530452
http://dx.doi.org/10.3390/biom11020159

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