Identification of Variants (rs11571707, rs144848, and rs11571769) in the BRCA2 Gene Associated with Hereditary Breast Cancer in Indigenous Populations of the Brazilian Amazon

Estimates show that 5–10% of breast cancer cases are hereditary, caused by genetic variants in autosomal dominant genes; of these, 16% are due to germline mutations in the BRCA1 and BRCA2 genes. The comprehension of the mutation profile of these genes in the Brazilian population, particularly in Ama...

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Detalles Bibliográficos
Autores principales: Dobbin, Elizabeth Ayres Fragoso, Medeiros, Jéssyca Amanda Gomes, Costa, Marta Solange Camarinha Ramos, Rodrigues, Juliana Carla Gomes, Guerreiro, João Farias, Kroll, José Eduardo, de Souza, Sandro José, de Assumpção, Paulo Pimentel, Ribeiro-dos-Santos, Ândrea, dos Santos, Sidney Emanuel Batista, Burbano, Rommel Mario Rodríguez, Fernandes, Marianne Rodrigues, dos Santos, Ney Pereira Carneiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7911168/
https://www.ncbi.nlm.nih.gov/pubmed/33499154
http://dx.doi.org/10.3390/genes12020142

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