Cargando…

Prevalence and Predictors of Vitamin D Deficiency and Insufficiency among Pregnant Rural Women in Bangladesh

Although adequate vitamin D status during pregnancy is essential for maternal health and to prevent adverse pregnancy outcomes, limited data exist on vitamin D status and associated risk factors in pregnant rural Bangladeshi women. This study determined the prevalence of vitamin D deficiency and ins...

Descripción completa

Detalles Bibliográficos
Autores principales: Ahmed, Faruk, Khosravi-Boroujeni, Hossein, Khan, Moududur Rahman, Roy, Anjan Kumar, Raqib, Rubhana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7911263/
https://www.ncbi.nlm.nih.gov/pubmed/33572898
http://dx.doi.org/10.3390/nu13020449
_version_ 1783656300369936384
author Ahmed, Faruk
Khosravi-Boroujeni, Hossein
Khan, Moududur Rahman
Roy, Anjan Kumar
Raqib, Rubhana
author_facet Ahmed, Faruk
Khosravi-Boroujeni, Hossein
Khan, Moududur Rahman
Roy, Anjan Kumar
Raqib, Rubhana
author_sort Ahmed, Faruk
collection PubMed
description Although adequate vitamin D status during pregnancy is essential for maternal health and to prevent adverse pregnancy outcomes, limited data exist on vitamin D status and associated risk factors in pregnant rural Bangladeshi women. This study determined the prevalence of vitamin D deficiency and insufficiency, and identified associated risk factors, among these women. A total of 515 pregnant women from rural Bangladesh, gestational age ≤ 20 weeks, participated in this cross-sectional study. A separate logistic regression analysis was applied to determine the risk factors of vitamin D deficiency and insufficiency. Overall, 17.3% of the pregnant women had vitamin D deficiency [serum 25(OH)D concentration <30.0 nmol/L], and 47.2% had vitamin D insufficiency [serum 25(OH)D concentration between 30–<50 nmol/L]. The risk of vitamin D insufficiency was significantly higher among nulliparous pregnant women (OR: 2.72; 95% CI: 1.75–4.23), those in their first trimester (OR: 2.68; 95% CI: 1.39–5.19), anaemic women (OR: 1.53; 95% CI: 0.99–2.35; p = 0.056) and women whose husbands are farmers (OR: 2.06; 95% CI: 1.22–3.50). The risk of vitamin deficiency was significantly higher among younger pregnant women (<25 years; OR: 2.12; 95% CI: 1.06–4.21), nulliparous women (OR: 2.65; 95% CI: 1.34–5.25), women in their first trimester (OR: 2.55; 95% CI: 1.12–5.79) and those with sub-optimal vitamin A status (OR: 2.30; 95% CI: 1.28–4.11). In conclusion, hypovitaminosis D is highly prevalent among pregnant rural Bangladeshi women. Parity and gestational age are the common risk factors of vitamin D deficiency and insufficiency. A husband’s occupation and anaemia status might be important predictors of vitamin D insufficiency, while younger age and sub-optimal vitamin A status are risk factors for vitamin D deficiency in this population.
format Online
Article
Text
id pubmed-7911263
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-79112632021-02-28 Prevalence and Predictors of Vitamin D Deficiency and Insufficiency among Pregnant Rural Women in Bangladesh Ahmed, Faruk Khosravi-Boroujeni, Hossein Khan, Moududur Rahman Roy, Anjan Kumar Raqib, Rubhana Nutrients Article Although adequate vitamin D status during pregnancy is essential for maternal health and to prevent adverse pregnancy outcomes, limited data exist on vitamin D status and associated risk factors in pregnant rural Bangladeshi women. This study determined the prevalence of vitamin D deficiency and insufficiency, and identified associated risk factors, among these women. A total of 515 pregnant women from rural Bangladesh, gestational age ≤ 20 weeks, participated in this cross-sectional study. A separate logistic regression analysis was applied to determine the risk factors of vitamin D deficiency and insufficiency. Overall, 17.3% of the pregnant women had vitamin D deficiency [serum 25(OH)D concentration <30.0 nmol/L], and 47.2% had vitamin D insufficiency [serum 25(OH)D concentration between 30–<50 nmol/L]. The risk of vitamin D insufficiency was significantly higher among nulliparous pregnant women (OR: 2.72; 95% CI: 1.75–4.23), those in their first trimester (OR: 2.68; 95% CI: 1.39–5.19), anaemic women (OR: 1.53; 95% CI: 0.99–2.35; p = 0.056) and women whose husbands are farmers (OR: 2.06; 95% CI: 1.22–3.50). The risk of vitamin deficiency was significantly higher among younger pregnant women (<25 years; OR: 2.12; 95% CI: 1.06–4.21), nulliparous women (OR: 2.65; 95% CI: 1.34–5.25), women in their first trimester (OR: 2.55; 95% CI: 1.12–5.79) and those with sub-optimal vitamin A status (OR: 2.30; 95% CI: 1.28–4.11). In conclusion, hypovitaminosis D is highly prevalent among pregnant rural Bangladeshi women. Parity and gestational age are the common risk factors of vitamin D deficiency and insufficiency. A husband’s occupation and anaemia status might be important predictors of vitamin D insufficiency, while younger age and sub-optimal vitamin A status are risk factors for vitamin D deficiency in this population. MDPI 2021-01-29 /pmc/articles/PMC7911263/ /pubmed/33572898 http://dx.doi.org/10.3390/nu13020449 Text en © 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Ahmed, Faruk
Khosravi-Boroujeni, Hossein
Khan, Moududur Rahman
Roy, Anjan Kumar
Raqib, Rubhana
Prevalence and Predictors of Vitamin D Deficiency and Insufficiency among Pregnant Rural Women in Bangladesh
title Prevalence and Predictors of Vitamin D Deficiency and Insufficiency among Pregnant Rural Women in Bangladesh
title_full Prevalence and Predictors of Vitamin D Deficiency and Insufficiency among Pregnant Rural Women in Bangladesh
title_fullStr Prevalence and Predictors of Vitamin D Deficiency and Insufficiency among Pregnant Rural Women in Bangladesh
title_full_unstemmed Prevalence and Predictors of Vitamin D Deficiency and Insufficiency among Pregnant Rural Women in Bangladesh
title_short Prevalence and Predictors of Vitamin D Deficiency and Insufficiency among Pregnant Rural Women in Bangladesh
title_sort prevalence and predictors of vitamin d deficiency and insufficiency among pregnant rural women in bangladesh
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7911263/
https://www.ncbi.nlm.nih.gov/pubmed/33572898
http://dx.doi.org/10.3390/nu13020449
work_keys_str_mv AT ahmedfaruk prevalenceandpredictorsofvitaminddeficiencyandinsufficiencyamongpregnantruralwomeninbangladesh
AT khosraviboroujenihossein prevalenceandpredictorsofvitaminddeficiencyandinsufficiencyamongpregnantruralwomeninbangladesh
AT khanmoududurrahman prevalenceandpredictorsofvitaminddeficiencyandinsufficiencyamongpregnantruralwomeninbangladesh
AT royanjankumar prevalenceandpredictorsofvitaminddeficiencyandinsufficiencyamongpregnantruralwomeninbangladesh
AT raqibrubhana prevalenceandpredictorsofvitaminddeficiencyandinsufficiencyamongpregnantruralwomeninbangladesh