A New Peracetylated Oleuropein Derivative Ameliorates Joint Inflammation and Destruction in a Murine Collagen-Induced Arthritis Model via Activation of the Nrf-2/Ho-1 Antioxidant Pathway and Suppression of MAPKs and NF-κB Activation

Oleuropein (OL), an olive tree secoiridoid and its peracetylated derivate (Per-OL) have exhibited several beneficial effects on LPS-stimulated macrophages and murine experimental systemic lupus erythematosus (SLE). This study was designed to evaluate dietary Per-OL in comparison with OL supplementat...

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Detalles Bibliográficos
Autores principales: Castejón, María Luisa, Alarcón-de-la-Lastra, Catalina, Rosillo, María Ángeles, Montoya, Tatiana, Fernández-Bolaños, Jose G., González-Benjumea, Alejandro, Sánchez-Hidalgo, Marina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7911327/
https://www.ncbi.nlm.nih.gov/pubmed/33499113
http://dx.doi.org/10.3390/nu13020311

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7911327/
https://www.ncbi.nlm.nih.gov/pubmed/33499113
http://dx.doi.org/10.3390/nu13020311

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