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A New Peracetylated Oleuropein Derivative Ameliorates Joint Inflammation and Destruction in a Murine Collagen-Induced Arthritis Model via Activation of the Nrf-2/Ho-1 Antioxidant Pathway and Suppression of MAPKs and NF-κB Activation
Oleuropein (OL), an olive tree secoiridoid and its peracetylated derivate (Per-OL) have exhibited several beneficial effects on LPS-stimulated macrophages and murine experimental systemic lupus erythematosus (SLE). This study was designed to evaluate dietary Per-OL in comparison with OL supplementat...
Autores principales: | Castejón, María Luisa, Alarcón-de-la-Lastra, Catalina, Rosillo, María Ángeles, Montoya, Tatiana, Fernández-Bolaños, Jose G., González-Benjumea, Alejandro, Sánchez-Hidalgo, Marina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7911327/ https://www.ncbi.nlm.nih.gov/pubmed/33499113 http://dx.doi.org/10.3390/nu13020311 |
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