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Moxifloxacin Activates the SOS Response in Mycobacterium tuberculosis in a Dose- and Time-Dependent Manner

Previous studies on Escherichia coli demonstrated that sub-minimum inhibitory concentration (MIC) of fluoroquinolones induced the SOS response, increasing drug tolerance. We characterized the transcriptional response to moxifloxacin in Mycobacterium tuberculosis. Reference strain H37Rv was treated w...

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Detalles Bibliográficos
Autores principales: Iacobino, Angelo, Piccaro, Giovanni, Pardini, Manuela, Fattorini, Lanfranco, Giannoni, Federico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7911356/
https://www.ncbi.nlm.nih.gov/pubmed/33513836
http://dx.doi.org/10.3390/microorganisms9020255