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Kisspeptin-8 Induces Anxiety-Like Behavior and Hypolocomotion by Activating the HPA Axis and Increasing GABA Release in the Nucleus Accumbens in Rats

Kisspeptins (Kp) are RF-amide neuropeptide regulators of the reproductive axis that also influence anxiety, locomotion, and metabolism. We aimed to investigate the effects of intracerebroventricular Kp-8 (an N-terminally truncated octapeptide) treatment in Wistar rats. Elevated plus maze (EPM), comp...

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Detalles Bibliográficos
Autores principales: Ibos, Katalin Eszter, Bodnár, Éva, Bagosi, Zsolt, Bozsó, Zsolt, Tóth, Gábor, Szabó, Gyula, Csabafi, Krisztina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7911394/
https://www.ncbi.nlm.nih.gov/pubmed/33503835
http://dx.doi.org/10.3390/biomedicines9020112