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ADAM10-Mediated Cleavage of ICAM-1 Is Involved in Neutrophil Transendothelial Migration
To efficiently cross the endothelial barrier during inflammation, neutrophils first firmly adhere to the endothelial surface using the endothelial adhesion molecule ICAM-1. Upon actual transmigration, the release from ICAM-1 is required. While Integrin LFA1/Mac1 de-activation is one described mechan...
Autores principales: | Morsing, Sofia K. H., Rademakers, Timo, Brouns, Sanne L. N., van Stalborch, Anne-Marieke D., Donners, Marjo M. P. C., van Buul, Jaap D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7911467/ https://www.ncbi.nlm.nih.gov/pubmed/33504031 http://dx.doi.org/10.3390/cells10020232 |
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