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An Update on Self-Amplifying mRNA Vaccine Development

This review will explore the four major pillars required for design and development of an saRNA vaccine: Antigen design, vector design, non-viral delivery systems, and manufacturing (both saRNA and lipid nanoparticles (LNP)). We report on the major innovations, preclinical and clinical data reported...

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Detalles Bibliográficos
Autores principales:	Blakney, Anna K., Ip, Shell, Geall, Andrew J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7911542/ https://www.ncbi.nlm.nih.gov/pubmed/33525396 http://dx.doi.org/10.3390/vaccines9020097

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