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Human Lectins, Their Carbohydrate Affinities and Where to Find Them

Lectins are a class of proteins responsible for several biological roles such as cell-cell interactions, signaling pathways, and several innate immune responses against pathogens. Since lectins are able to bind to carbohydrates, they can be a viable target for targeted drug delivery systems. In fact...

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Detalles Bibliográficos
Autores principales: Raposo, Cláudia D., Canelas, André B., Barros, M. Teresa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7911577/
https://www.ncbi.nlm.nih.gov/pubmed/33572889
http://dx.doi.org/10.3390/biom11020188
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author Raposo, Cláudia D.
Canelas, André B.
Barros, M. Teresa
author_facet Raposo, Cláudia D.
Canelas, André B.
Barros, M. Teresa
author_sort Raposo, Cláudia D.
collection PubMed
description Lectins are a class of proteins responsible for several biological roles such as cell-cell interactions, signaling pathways, and several innate immune responses against pathogens. Since lectins are able to bind to carbohydrates, they can be a viable target for targeted drug delivery systems. In fact, several lectins were approved by Food and Drug Administration for that purpose. Information about specific carbohydrate recognition by lectin receptors was gathered herein, plus the specific organs where those lectins can be found within the human body.
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spelling pubmed-79115772021-02-28 Human Lectins, Their Carbohydrate Affinities and Where to Find Them Raposo, Cláudia D. Canelas, André B. Barros, M. Teresa Biomolecules Review Lectins are a class of proteins responsible for several biological roles such as cell-cell interactions, signaling pathways, and several innate immune responses against pathogens. Since lectins are able to bind to carbohydrates, they can be a viable target for targeted drug delivery systems. In fact, several lectins were approved by Food and Drug Administration for that purpose. Information about specific carbohydrate recognition by lectin receptors was gathered herein, plus the specific organs where those lectins can be found within the human body. MDPI 2021-01-29 /pmc/articles/PMC7911577/ /pubmed/33572889 http://dx.doi.org/10.3390/biom11020188 Text en © 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Raposo, Cláudia D.
Canelas, André B.
Barros, M. Teresa
Human Lectins, Their Carbohydrate Affinities and Where to Find Them
title Human Lectins, Their Carbohydrate Affinities and Where to Find Them
title_full Human Lectins, Their Carbohydrate Affinities and Where to Find Them
title_fullStr Human Lectins, Their Carbohydrate Affinities and Where to Find Them
title_full_unstemmed Human Lectins, Their Carbohydrate Affinities and Where to Find Them
title_short Human Lectins, Their Carbohydrate Affinities and Where to Find Them
title_sort human lectins, their carbohydrate affinities and where to find them
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7911577/
https://www.ncbi.nlm.nih.gov/pubmed/33572889
http://dx.doi.org/10.3390/biom11020188
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