Cargando…

Novel Approaches to Epigenetic Therapies: From Drug Combinations to Epigenetic Editing

Cancer development involves both genetic and epigenetic alterations. Aberrant epigenetic modifications are reversible, allowing excellent opportunities for therapeutic intervention. Nowadays, several epigenetic drugs are used worldwide to treat, e.g., myelodysplastic syndromes and leukemias. However...

Descripción completa

Detalles Bibliográficos
Autores principales:	Majchrzak-Celińska, Aleksandra, Warych, Anna, Szoszkiewicz, Mikołaj
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7911730/ https://www.ncbi.nlm.nih.gov/pubmed/33572577 http://dx.doi.org/10.3390/genes12020208

Ejemplares similares

Epigenetic polypharmacology: from combination therapy to multitargeted drugs
por: de Lera, Angel R., et al.
Publicado: (2016)

Current Approaches to Epigenetic Therapy
por: Griazeva, Ekaterina D., et al.
Publicado: (2023)

The Epigenetic Profile of Tumor Endothelial Cells. Effects of Combined Therapy with Antiangiogenic and Epigenetic Drugs on Cancer Progression
por: Ciesielski, Oskar, et al.
Publicado: (2020)

Cannabidiol and Its Combinations with Nonsteroidal Anti-Inflammatory Drugs Induce Apoptosis and Inhibit Activation of NF-κB Signaling in Vulvar Squamous Cell Carcinoma
por: Krajka-Kuźniak, Violetta, et al.
Publicado: (2022)

Correction of Heritable Epigenetic Defects Using Editing Tools
por: Handal, Tayma, et al.
Publicado: (2021)

Mutations in Epigenetic Modifiers in Myeloid Malignancies and the Prospect of Novel Epigenetic-Targeted Therapy
por: Fathi, Amir T., et al.
Publicado: (2012)

Epigenetic synthetic lethality approaches in cancer therapy
por: Yang, Haoshen, et al.
Publicado: (2019)

Drug screening approach combines epigenetic sensitization with immunochemotherapy in cancer
por: Facciotto, Chiara, et al.
Publicado: (2019)

Genetic and epigenetic editing in nervous system 
por: Day, Jeremy J.
Publicado: (2019)

OMICs, Epigenetics, and Genome Editing Techniques for Food and Nutritional Security
por: Gogolev, Yuri V., et al.
Publicado: (2021)

Insights into novel emerging epigenetic drugs in myeloid malignancies
por: Chandhok, Namrata S., et al.
Publicado: (2019)

Advances in Ophthalmic Epigenetics and Implications for Epigenetic Therapies: A Review
por: Moore, Spencer M., et al.
Publicado: (2023)

Reprogramming the anti-tumor immune response via CRISPR genetic and epigenetic editing
por: Alves, Eric, et al.
Publicado: (2021)

Lichen Secondary Metabolites Inhibit the Wnt/β-Catenin Pathway in Glioblastoma Cells and Improve the Anticancer Effects of Temozolomide
por: Majchrzak-Celińska, Aleksandra, et al.
Publicado: (2022)

Novel epigenetic molecular therapies for imprinting disorders
por: Wang, Sung Eun, et al.
Publicado: (2023)

Novel insights into histone lysine methyltransferases in cancer therapy: From epigenetic regulation to selective drugs
por: Liao, Qili, et al.
Publicado: (2023)

A Novel Epi-drug Therapy Based on the Suppression of BET Family Epigenetic Readers
por: Shin, Dong-Guk, et al.
Publicado: (2017)

Epigenetic Effects of Drugs of Abuse
por: Heinbockel, Thomas, et al.
Publicado: (2018)

Epigenetic Editing: targeted rewriting of epigenetic marks to modulate expression of selected target genes
por: de Groote, Marloes L., et al.
Publicado: (2012)

Brain Tumors: Development, Drug Resistance, and Sensitization – An Epigenetic Approach
por: Sarkar, Sibaji, et al.
Publicado: (2023)

Modeling epigenetic modifications in renal development and disease with organoids and genome editing
por: Hurtado del Pozo, Carmen, et al.
Publicado: (2018)

Epigenetic editing and tumor-dependent immunosuppressive signaling in head and neck malignancies
por: Gougousis, Spyridon, et al.
Publicado: (2022)

Advances of Epigenetic Biomarkers and Epigenome Editing for Early Diagnosis in Breast Cancer
por: Sarvari, Pourya, et al.
Publicado: (2022)

Epigenetic Editing: On the Verge of Reprogramming Gene Expression at Will
por: Cano-Rodriguez, David, et al.
Publicado: (2016)

Epigenetic therapy combinations in acute myeloid leukemia: what are the options?
por: Bewersdorf, Jan Philipp, et al.
Publicado: (2019)

Epigenetic Modifications: Novel Therapeutic Approach for Thyroid Cancer
por: Zhu, Xuguang, et al.
Publicado: (2017)

Epigenetics: Novel crucial approach for osteogenesis of mesenchymal stem cells
por: Wang, Zhaohua, et al.
Publicado: (2023)

The Role of Epigenetics in the Induction of Fetal Hemoglobin: A Combination Therapy Approach
por: Ahmadvand, Mohammad, et al.
Publicado: (2014)

Epigenetic Therapy in Human Choriocarcinoma
por: Takai, Noriyuki, et al.
Publicado: (2010)

Targeting epigenetics for cancer therapy
por: Park, Jong Woo, et al.
Publicado: (2019)

Advances in epigenetic glioblastoma therapy
por: Lee, Dong Hoon, et al.
Publicado: (2017)

Epigenetics in cancer therapy and nanomedicine
por: Roberti, Annalisa, et al.
Publicado: (2019)

PPARα in the Epigenetic Driver Seat of NAFLD: New Therapeutic Opportunities for Epigenetic Drugs?
por: Theys, Claudia, et al.
Publicado: (2022)

Hydroxymethylation and Epigenetic Drugs: New Insights into the Diagnosis and Treatment in Epigenetics of Hepatocellular Carcinoma
por: Ouyang, Wei, et al.
Publicado: (2023)

DNA methylation analysis with methylation‐sensitive high‐resolution melting (MS‐HRM) reveals gene panel for glioma characteristics
por: Majchrzak‐Celińska, Aleksandra, et al.
Publicado: (2020)

Use of Epigenetic Drugs in Disease: An Overview
por: Heerboth, Sarah, et al.
Publicado: (2014)

Epigenetic regulation of drug metabolism and transport
por: Peng, Lai, et al.
Publicado: (2015)

Epigenetic Regulation of Antifungal Drug Resistance
por: Patra, Sandip, et al.
Publicado: (2022)

The timeline of epigenetic drug discovery: from reality to dreams
por: Ganesan, A., et al.
Publicado: (2019)

Genetics and Epigenetics of Myelodysplastic Syndromes and Response to Drug Therapy: New Insights
por: Shahrabi, Saeid, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_2tvvfi6kr60ce8jki3dgdlc548