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Discovery of Survivin Inhibitors Part 1: Screening the Harbor Branch Pure Compound Library
Survivin is a 16.5 KDa protein whose functions include promoting cellular mitosis, angiogenesis, and senescence as well as inhibiting apoptosis. Higher survivin expression is found in cancer tissues than normal tissues, and this expression correlates with disease progression and aggressiveness. Surv...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7911841/ https://www.ncbi.nlm.nih.gov/pubmed/33573152 http://dx.doi.org/10.3390/md19020073 |