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ER Stress and Unfolded Protein Response in Leukemia: Friend, Foe, or Both?

The unfolded protein response (UPR) is an evolutionarily conserved adaptive signaling pathway triggered by a stress of the endoplasmic reticulum (ER) lumen compartment, which is initiated by the accumulation of unfolded proteins. This response, mediated by three sensors-Inositol Requiring Enzyme 1 (...

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Detalles Bibliográficos
Autores principales: Féral, Kelly, Jaud, Manon, Philippe, Céline, Di Bella, Doriana, Pyronnet, Stéphane, Rouault-Pierre, Kevin, Mazzolini, Laurent, Touriol, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7911881/
https://www.ncbi.nlm.nih.gov/pubmed/33573353
http://dx.doi.org/10.3390/biom11020199