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Co-Amorphous Formulations of Furosemide with Arginine and P-Glycoprotein Inhibitor Drugs

In this study, the amino acid arginine (ARG) and P-glycoprotein (P-gp) inhibitors verapamil hydrochloride (VER), piperine (PIP) and quercetin (QRT) were used as co-formers for co-amorphous mixtures of a Biopharmaceutics classification system (BCS) class IV drug, furosemide (FUR). FUR mixtures with V...

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Detalles Bibliográficos
Autores principales: Ruponen, Marika, Kettunen, Konsta, Santiago Pires, Monica, Laitinen, Riikka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7912042/
https://www.ncbi.nlm.nih.gov/pubmed/33514009
http://dx.doi.org/10.3390/pharmaceutics13020171