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EpCAM (CD326) Regulates Intestinal Epithelial Integrity and Stem Cells via Rho-Associated Kinase

Humans with biallelic inactivating mutations in Epithelial Cell Adhesion Molecule (EpCAM) develop congenital tufting enteropathy (CTE). To gain mechanistic insights regarding EpCAM function in this disorder, we prepared intestinal epithelial cell (IEC) organoids and spheroids. IEC organoids and sphe...

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Detalles Bibliográficos
Autores principales:	Ouchi, Takeshi, Morimura, Sohshi, Dow, Lukas E., Miyoshi, Hiroyuki, Udey, Mark C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7912093/ https://www.ncbi.nlm.nih.gov/pubmed/33525555 http://dx.doi.org/10.3390/cells10020256

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