From Transcriptomics to Treatment in Inherited Optic Neuropathies

Inherited optic neuropathies, including Leber Hereditary Optic Neuropathy (LHON) and Dominant Optic Atrophy (DOA), are monogenetic diseases with a final common pathway of mitochondrial dysfunction leading to retinal ganglion cell (RGC) death and ultimately loss of vision. They are, therefore, excell...

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Detalles Bibliográficos
Autores principales: Gilhooley, Michael James, Owen, Nicholas, Moosajee, Mariya, Yu Wai Man, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7912133/
https://www.ncbi.nlm.nih.gov/pubmed/33499292
http://dx.doi.org/10.3390/genes12020147

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7912133/
https://www.ncbi.nlm.nih.gov/pubmed/33499292
http://dx.doi.org/10.3390/genes12020147

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