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From Transcriptomics to Treatment in Inherited Optic Neuropathies

Inherited optic neuropathies, including Leber Hereditary Optic Neuropathy (LHON) and Dominant Optic Atrophy (DOA), are monogenetic diseases with a final common pathway of mitochondrial dysfunction leading to retinal ganglion cell (RGC) death and ultimately loss of vision. They are, therefore, excell...

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Detalles Bibliográficos
Autores principales:	Gilhooley, Michael James, Owen, Nicholas, Moosajee, Mariya, Yu Wai Man, Patrick
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7912133/ https://www.ncbi.nlm.nih.gov/pubmed/33499292 http://dx.doi.org/10.3390/genes12020147

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