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Small Molecule-Based Enzyme Inhibitors in the Treatment of Primary Hyperoxalurias
Primary hyperoxalurias (PHs) are a group of inherited alterations of the hepatic glyoxylate metabolism. PHs classification based on gene mutations parallel a variety of enzymatic defects, and all involve the harmful accumulation of calcium oxalate crystals that produce systemic damage. These geograp...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7912158/ https://www.ncbi.nlm.nih.gov/pubmed/33513899 http://dx.doi.org/10.3390/jpm11020074 |