Cargando…

Drug Disposition in the Lower Gastrointestinal Tract: Targeting and Monitoring

The increasing prevalence of colonic diseases calls for a better understanding of the various colonic drug absorption barriers of colon-targeted formulations, and for reliable in vitro tools that accurately predict local drug disposition. In vivo relevant incubation conditions have been shown to bet...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lemmens, Glenn, Van Camp, Arno, Kourula, Stephanie, Vanuytsel, Tim, Augustijns, Patrick
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7912393/ https://www.ncbi.nlm.nih.gov/pubmed/33530468 http://dx.doi.org/10.3390/pharmaceutics13020161

Ejemplares similares

Racial Disparity in Drug Disposition in the Digestive Tract
por: Gao, Song, et al.
Publicado: (2021)

Animal Models for Functional Gastrointestinal Disorders
por: Accarie, Alison, et al.
Publicado: (2020)

A Tutorial on Target-Mediated Drug Disposition (TMDD) Models
por: Dua, P, et al.
Publicado: (2015)

Characterization of Aspirated Duodenal Fluids from Parkinson’s Disease Patients
por: de Waal, Tom, et al.
Publicado: (2023)

The Role of Intestinal Permeability in Gastrointestinal Disorders and Current Methods of Evaluation
por: Vanuytsel, Tim, et al.
Publicado: (2021)

Serotonin and Melatonin in Human Lower Gastrointestinal Tract
por: Vaccaro, Rosa, et al.
Publicado: (2023)

Sex Differences in Drug Disposition
por: Soldin, Offie P., et al.
Publicado: (2011)

Lower gastrointestinal tract tumours: diagnosis and staging strategies
por: Gore, Richard M
Publicado: (2005)

Physiologic Status Monitoring via the Gastrointestinal Tract
por: Traverso, G., et al.
Publicado: (2015)

Dynamics of target-mediated drug disposition: characteristic profiles and parameter identification
por: Peletier, Lambertus A., et al.
Publicado: (2012)

Target Mediated Drug Disposition Model of CPHPC in Patients with Systemic Amyloidosis
por: Sahota, T, et al.
Publicado: (2015)

Bioadhesive Bacterial Microswimmers for Targeted Drug Delivery in the Urinary and Gastrointestinal Tracts
por: Mostaghaci, Babak, et al.
Publicado: (2017)

Investigating Tacrolimus Disposition in Paediatric Patients with a Physiologically Based Pharmacokinetic Model Incorporating CYP3A4 Ontogeny, Mechanistic Absorption and Red Blood Cell Binding
por: Van der Veken, Matthias, et al.
Publicado: (2023)

Gastrointestinal Fluid Volumes in Pediatrics: A Retrospective MRI Study
por: Van der Veken, Matthias, et al.
Publicado: (2022)

The Yearly Prevalence of Findings in Endoscopy of the Lower Part of the Gastrointestinal Tract
por: Loffeld, R. J. L. F., et al.
Publicado: (2012)

The Effects of Eupatilin (Stillen®) on Motility of Human Lower Gastrointestinal Tracts
por: Ryoo, Seung-Bum, et al.
Publicado: (2014)

Localization and function of NO-GC in the murine gastrointestinal and lower urinary tract
por: Lies, Barbara, et al.
Publicado: (2013)

Potential Strategies in the Prevention of Nonsteroidal Anti-inflammatory Drugs-Associated Adverse Effects in the Lower Gastrointestinal Tract
por: Guo, Chuan-Guo, et al.
Publicado: (2020)

Reduced and optimized trial designs for drugs described by a target mediated drug disposition model
por: Brekkan, A., et al.
Publicado: (2018)

A mathematical analysis of rebound in a target-mediated drug disposition model: II. With feedback
por: Aston, Philip J., et al.
Publicado: (2016)

Treatment With Antipsychotics in Pregnancy: Changes in Drug Disposition
por: Westin, Andreas A., et al.
Publicado: (2017)

The Dynamic Intestinal Absorption Model (Diamod®), an in vitro tool to study the interconnected kinetics of gastrointestinal solubility, supersaturation, precipitation, and intestinal permeation processes of oral drugs
por: Moens, Frédéric, et al.
Publicado: (2023)

Lower Urinary Tract and Gastrointestinal Dysfunction Are Common in Early Parkinson's Disease
por: Martinez-Ramirez, Daniel, et al.
Publicado: (2020)

Loose Screws: Removal of Foreign Bodies From the Lower Gastrointestinal Tract
por: Hardy, John C, et al.
Publicado: (2023)

Smart capsule for monitoring inflammation profile throughout the gastrointestinal tract
por: Gopalakrishnan, Sarath, et al.
Publicado: (2023)

Targeting CLDN18.2 in cancers of the gastrointestinal tract: New drugs and new indications
por: Chen, Jinxia, et al.
Publicado: (2023)

Targeting cancers in the gastrointestinal tract: role of capecitabine
por: Saif, Muhammad Wasif
Publicado: (2009)

Dispositions : a debate /
por: Armstrong, D. M. (David Malet), 1926-
Publicado: (1996)

In vitro and in vivo drug disposition of cilengitide in animals and human
por: Dolgos, Hugues, et al.
Publicado: (2016)

Development of Human Membrane Transporters: Drug Disposition and Pharmacogenetics
por: Mooij, Miriam G., et al.
Publicado: (2015)

Challenges and advances in the assessment of the disposition of antibody‐drug conjugates
por: Kamath, Amrita V., et al.
Publicado: (2015)

Editorial of Special Issue on Drug Metabolism and Disposition in Diseases
por: Xie, Wen
Publicado: (2020)

Disposition générale
Publicado: (1966)

Representing dispositions
por: Röhl, Johannes, et al.
Publicado: (2011)

Drug-disease interaction: Clinical consequences of inflammation on drugs action and disposition
por: Abdallah, Yasmeen El Hajj, et al.
Publicado: (2023)

Oral Drug Absorption and Drug Disposition in Critically Ill Cardiac Patients
por: Harnisch, Lars-Olav, et al.
Publicado: (2023)

Individual Variations in the Absorption of Drugs from the Gastrointestinal Tract
por: Chopra, R. N., et al.
Publicado: (1945)

An Overview of Robotic Capsules for Drug Delivery to the Gastrointestinal Tract
por: Cortegoso Valdivia, Pablo, et al.
Publicado: (2021)

Target‐Mediated Drug Disposition Model for Bispecific Antibodies: Properties, Approximation, and Optimal Dosing Strategy
por: Schropp, Johannes, et al.
Publicado: (2019)

Endoscopic electrocautery incision therapy for benign lower gastrointestinal tract anastomotic strictures
por: Jain, Deepanshu, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_ubm6qumg8r1nun283fgcrq26kd