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Osthole enhances the bone mass of senile osteoporosis and stimulates the expression of osteoprotegerin by activating β-catenin signaling

INTRODUCTION: Osthole has a potential therapeutic application for anti-osteoporosis. The present study verified whether osthole downregulates osteoclastogenesis via targeting OPG. METHODS: In vivo, 12-month-old male mice were utilized to evaluate the effect of osthole on bone mass. In vitro, bone ma...

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Detalles Bibliográficos
Autores principales:	Jin, Zhen-Xiong, Liao, Xin-Yuan, Da, Wei-Wei, Zhao, Yong-Jian, Li, Xiao-Feng, Tang, De-Zhi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7912492/ https://www.ncbi.nlm.nih.gov/pubmed/33640026 http://dx.doi.org/10.1186/s13287-021-02228-6

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