Knockout of myoc Provides Evidence for the Role of Myocilin in Zebrafish Sex Determination Associated with Wnt Signalling Downregulation

SIMPLE SUMMARY: Myocilin is a protein with an incompletely understood function, mainly known because of its role in glaucoma. In this study we have analysed the normal role of this protein in vivo. To that end, we generated the first myocilin knockout zebrafish line reported to date. This zebrafish...

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Detalles Bibliográficos
Autores principales: Atienzar-Aroca, Raquel, Aroca-Aguilar, José-Daniel, Alexandre-Moreno, Susana, Ferre-Fernández, Jesús-José, Bonet-Fernández, Juan-Manuel, Cabañero-Varela, María-José, Escribano, Julio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7912607/
https://www.ncbi.nlm.nih.gov/pubmed/33573230
http://dx.doi.org/10.3390/biology10020098

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7912607/
https://www.ncbi.nlm.nih.gov/pubmed/33573230
http://dx.doi.org/10.3390/biology10020098

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