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Phosphorylation of Microglial IRF5 and IRF4 by IRAK4 Regulates Inflammatory Responses to Ischemia

Background: Interferon Regulatory Factor (IRF) 5 and 4 play a determinant role in regulating microglial pro- and anti-inflammatory responses to cerebral ischemia. How microglial IRF5 and IRF4 signaling are activated has been elusive. We hypothesized that interleukin-1 receptor associated kinase 4 (I...

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Detalles Bibliográficos
Autores principales:	Ngwa, Conelius, Mamun, Abdullah Al, Xu, Yan, Sharmeen, Romana, Liu, Fudong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7912637/ https://www.ncbi.nlm.nih.gov/pubmed/33573200 http://dx.doi.org/10.3390/cells10020276

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