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IRE1 Alpha/XBP1 Axis Sustains Primary Effusion Lymphoma Cell Survival by Promoting Cytokine Release and STAT3 Activation

Primary Effusion Lymphoma (PEL) is a highly aggressive B cell lymphoma associated with Kaposi’s Sarcoma-associated Herpesvirus (KSHV). It is characterized by a high level of basal Endoplasmic Reticulum (ER) stress, Unfolded Protein Response (UPR) activation and constitutive phosphorylation of oncoge...

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Detalles Bibliográficos
Autores principales:	Gonnella, Roberta, Gilardini Montani, Maria Saveria, Guttieri, Luisa, Romeo, Maria Anele, Santarelli, Roberta, Cirone, Mara
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7912693/ https://www.ncbi.nlm.nih.gov/pubmed/33513694 http://dx.doi.org/10.3390/biomedicines9020118

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