Cargando…

Tetrahydrofurofuranoid Lignans, Eudesmin, Fargesin, Epimagnolin A, Magnolin, and Yangambin Inhibit UDP-Glucuronosyltransferase 1A1 and 1A3 Activities in Human Liver Microsomes

Eudesmin, fargesin, epimagnolin A, magnolin, and yangambin are tetrahydrofurofuranoid lignans with various pharmacological activities found in Magnoliae Flos. The inhibition potencies of eudesmin, fargesin, epimagnolin A, magnolin, and yangambin on six major human uridine 5′-diphospho-glucuronosyltr...

Descripción completa

Detalles Bibliográficos
Autores principales:	Park, Ria, Park, Eun Jeong, Cho, Yong-Yeon, Lee, Joo Young, Kang, Han Chang, Song, Im-Sook, Lee, Hye Suk
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7912740/ https://www.ncbi.nlm.nih.gov/pubmed/33535454 http://dx.doi.org/10.3390/pharmaceutics13020187

Ejemplares similares

Inhibitory Effects of Dimethyllirioresinol, Epimagnolin A, Eudesmin, Fargesin, and Magnolin on Cytochrome P450 Enzyme Activities in Human Liver Microsomes
por: Kim, Ju-Hyun, et al.
Publicado: (2017)

In vitro leishmanicidal effect of Yangambin and Epi-yangambin lignans isolated from Ocotea fasciculata (Nees) Mez
por: Rebouças-Silva, Jéssica, et al.
Publicado: (2023)

Anticancer Potentials of the Lignan Magnolin: A Systematic Review
por: Bhuia, Md. Shimul, et al.
Publicado: (2023)

In Vitro Glucuronidation of Wushanicaritin by Liver Microsomes, Intestine Microsomes and Expressed Human UDP-Glucuronosyltransferase Enzymes
por: Hong, Xiaodan, et al.
Publicado: (2017)

Glucuronidation of drugs in humanized UDP-glucuronosyltransferase 1 mice: Similarity with glucuronidation in human liver microsomes
por: Kutsuno, Yuki, et al.
Publicado: (2013)

Modulation of Chloride Channel Functions by the Plant Lignan Compounds Kobusin and Eudesmin
por: Jiang, Yu, et al.
Publicado: (2015)

Effect of Honokiol on Cytochrome P450 and UDP-Glucuronosyltransferase Enzyme Activities in Human Liver Microsomes
por: Jeong, Hyeon-Uk, et al.
Publicado: (2013)

Effect of Efavirenz on UDP-Glucuronosyltransferase 1A1, 1A4, 1A6, and 1A9 Activities in Human Liver Microsomes
por: Ji, Hye Young, et al.
Publicado: (2012)

Corydaline Inhibits Multiple Cytochrome P450 and UDP-Glucuronosyltransferase Enzyme Activities in Human Liver Microsomes
por: Ji, Hye Young, et al.
Publicado: (2011)

Exploring the Metabolism of Loxoprofen in Liver Microsomes: The Role of Cytochrome P450 and UDP-Glucuronosyltransferase in Its Biotransformation
por: Shrestha, Riya, et al.
Publicado: (2018)

Characterization of the metabolism of fenretinide by human liver microsomes, cytochrome P450 enzymes and UDP-glucuronosyltransferases
por: Illingworth, NA, et al.
Publicado: (2011)

Identification of Human UDP-Glucuronosyltransferase 1A4 as the Major Isozyme Responsible for the Glucuronidation of 20(S)-Protopanaxadiol in Human Liver Microsomes
por: Li, Jia, et al.
Publicado: (2016)

Developmental increases in rat hepatic microsomal UDP-glucuronosyltransferase activities toward xenoestrogens and decreases during pregnancy.
por: Matsumoto, Junya, et al.
Publicado: (2002)

Expression of UDP-glucuronosyltransferase 1A4 in human placenta at term
por: Reimers, Arne, et al.
Publicado: (2010)

In Vitro Inhibitory Effects of Synthetic Cannabinoid EAM-2201 on Cytochrome P450 and UDP-Glucuronosyltransferase Enzyme Activities in Human Liver Microsomes
por: Kong, Tae Yeon, et al.
Publicado: (2018)

Traditional Herbal Formulas to as Treatments for Musculoskeletal Disorders: Their Inhibitory Effects on the Activities of Human Microsomal Cytochrome P450s and UDP-glucuronosyltransferases
por: Jin, Seong Eun, et al.
Publicado: (2016)

Magnolin Inhibits Paclitaxel-Induced Cold Allodynia and ERK1/2 Activation in Mice
por: Kim, Nari, et al.
Publicado: (2023)

Is Ceftriaxone-Induced Biliary Pseudolithiasis Influenced by UDP-Glucuronosyltransferase 1A1 Gene Polymorphisms?
por: Fretzayas, Andrew, et al.
Publicado: (2011)

Comparison of the inhibition potentials of icotinib and erlotinib against human UDP-glucuronosyltransferase 1A1
por: Cheng, Xuewei, et al.
Publicado: (2017)

Regulation of Sulfotransferase and UDP-Glucuronosyltransferase Gene Expression by the PPARs
por: Runge-Morris, Melissa, et al.
Publicado: (2009)

Structure and Protein–Protein Interactions of Human UDP-Glucuronosyltransferases
por: Fujiwara, Ryoichi, et al.
Publicado: (2016)

UDP-glucuronosyltransferases and biochemical recurrence in prostate cancer progression
por: Grant, Delores J., et al.
Publicado: (2017)

Quantitative analysis of the UDP‐glucuronosyltransferase transcriptome in human tissues
por: Zhou, Lucas, et al.
Publicado: (2023)

Glucose induces intestinal human UDP-glucuronosyltransferase (UGT) 1A1 to prevent neonatal hyperbilirubinemia
por: Aoshima, Naoya, et al.
Publicado: (2014)

Role of UDP-Glucuronosyltransferase 1A1 in the Metabolism and Pharmacokinetics of Silymarin Flavonolignans in Patients with HCV and NAFLD
por: Xie, Ying, et al.
Publicado: (2017)

Effects of Dietary Components on Testosterone Metabolism via UDP-Glucuronosyltransferase
por: Jenkinson, Carl, et al.
Publicado: (2013)

The Inhibition of the Components from Shengmai Injection towards UDP-Glucuronosyltransferase
por: Jiang, Li-Peng, et al.
Publicado: (2014)

Comparison of the Inhibitory Potential of Bavachalcone and Corylin against UDP-Glucuronosyltransferases
por: Shan, Lina, et al.
Publicado: (2014)

Emerging roles for UDP-glucuronosyltransferases in drug resistance and cancer progression
por: Allain, Eric P., et al.
Publicado: (2020)

Dysregulated hepatic UDP-glucuronosyltransferases and flavonoids glucuronidation in experimental colitis
por: Zeng, Wanying, et al.
Publicado: (2022)

The Functionality of UDP-Glucuronosyltransferase Genetic Variants and their Association with Drug Responses and Human Diseases
por: Jarrar, Yazun, et al.
Publicado: (2021)

Mertansine Inhibits mRNA Expression and Enzyme Activities of Cytochrome P450s and Uridine 5′-Diphospho-Glucuronosyltransferases in Human Hepatocytes and Liver Microsomes
por: Choi, Won-Gu, et al.
Publicado: (2020)

Impact of fatty acids on human UDP-glucuronosyltransferase 1A1 activity and its expression in neonatal hyperbilirubinemia
por: Shibuya, Ayako, et al.
Publicado: (2013)

Effect of a New Prokinetic Agent DA-9701 Formulated with Corydalis Tuber and Pharbitidis Semen on Cytochrome P450 and UDP-Glucuronosyltransferase Enzyme Activities in Human Liver Microsomes
por: Ji, Hye Young, et al.
Publicado: (2012)

Genetic Polymorphisms of the UDP‐Glucuronosyltransferase 1A7 Gene and Irinotecan Toxicity in Japanese Cancer Patients
por: Ando, Maki, et al.
Publicado: (2002)

Metabolic inactivation of estrogens in breast tissue by UDP-glucuronosyltransferase enzymes: an overview
por: Guillemette, Chantal, et al.
Publicado: (2004)

The UDP-glucuronosyltransferases of the blood-brain barrier: their role in drug metabolism and detoxication
por: Ouzzine, Mohamed, et al.
Publicado: (2014)

Fluid intake, genetic variants of UDP-glucuronosyltransferases, and bladder cancer risk
por: Wang, J, et al.
Publicado: (2013)

Endogenous Protein Interactome of Human UDP-Glucuronosyltransferases Exposed by Untargeted Proteomics
por: Rouleau, Michèle, et al.
Publicado: (2017)

Age-Dependent Hepatic UDP-Glucuronosyltransferase Gene Expression and Activity in Children
por: Neumann, Elizabeth, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_0tuskbattvqdt3gedab8b6i0vv