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Pancreastatin Reduces Alternatively Activated Macrophages, Disrupts the Epithelial Homeostasis and Aggravates Colonic Inflammation. A Descriptive Analysis
Ulcerative colitis (UC) is characterized by modifying alternatively activated macrophages (AAM) and epithelial homeostasis. Chromogranin-A (CHGA), released by enterochromaffin cells, is elevated in UC and is implicated in inflammation progression. CHGA can be cleaved into several derived peptides, i...
Autores principales: | Eissa, Nour, Elgazzar, Omar, Hussein, Hayam, Hendy, Geoffrey N., Bernstein, Charles N., Ghia, Jean-Eric |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7912769/ https://www.ncbi.nlm.nih.gov/pubmed/33535452 http://dx.doi.org/10.3390/biomedicines9020134 |
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