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Optimization of whole-genome sequencing of Plasmodium falciparum from low-density dried blood spot samples

BACKGROUND: Whole-genome sequencing (WGS) is becoming increasingly useful to study the biology, epidemiology, and ecology of malaria parasites. Despite ease of sampling, DNA extracted from dried blood spots (DBS) has a high ratio of human DNA compared to parasite DNA, which poses a challenge for dow...

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Detalles Bibliográficos
Autores principales:	Teyssier, Noam B., Chen, Anna, Duarte, Elias M., Sit, Rene, Greenhouse, Bryan, Tessema, Sofonias K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Methodology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7912882/ https://www.ncbi.nlm.nih.gov/pubmed/33637093 http://dx.doi.org/10.1186/s12936-021-03630-4

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