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Detection of gene fusions using targeted next-generation sequencing: a comparative evaluation

BACKGROUND: Gene fusions represent promising targets for cancer therapy in lung cancer. Reliable detection of multiple gene fusions is therefore essential. METHODS: Five commercially available parallel sequencing assays were evaluated for their ability to detect gene fusions in eight cell lines and...

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Detalles Bibliográficos
Autores principales:	Heydt, Carina, Wölwer, Christina B., Velazquez Camacho, Oscar, Wagener-Ryczek, Svenja, Pappesch, Roberto, Siemanowski, Janna, Rehker, Jan, Haller, Florian, Agaimy, Abbas, Worm, Karl, Herold, Thomas, Pfarr, Nicole, Weichert, Wilko, Kirchner, Thomas, Jung, Andreas, Kumbrink, Jörg, Goering, Wolfgang, Esposito, Irene, Buettner, Reinhard, Hillmer, Axel M., Merkelbach-Bruse, Sabine
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7912891/ https://www.ncbi.nlm.nih.gov/pubmed/33639937 http://dx.doi.org/10.1186/s12920-021-00909-y

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