Colonisation Factor CD0873, an Attractive Oral Vaccine Candidate against Clostridioides difficile

Clostridioides difficile is the main cause of health-care-associated infectious diarrhoea. Toxins, TcdA and TcdB, secreted by this bacterium damage colonic epithelial cells and in severe cases this culminates in pseudomembranous colitis, toxic megacolon and death. Vaccines in human trials have focus...

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Detalles Bibliográficos
Autores principales: Karyal, Cansu, Hughes, Jaime, Kelly, Michelle L., Luckett, Jeni C., Kaye, Philip V., Cockayne, Alan, Minton, Nigel P., Griffin, Ruth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7913071/
https://www.ncbi.nlm.nih.gov/pubmed/33540694
http://dx.doi.org/10.3390/microorganisms9020306

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