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Vaccine-Related Errors in Reconstitution in South Korea: A National Physicians’ and Nurses’ Survey

Vaccine-related errors (VREs) result from mistakes in vaccine preparation, handling, storage, or administration. We aimed to assess physicians’ and nurses’ experiences of VREs in South Korea, focusing on reconstitution issues, and to understand the barriers to and facilitators of preventing them. Th...

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Autores principales: Lee, Young Hwa, Harris, Rebecca C., Oh, Hong Won, Oh, Yongho, Vargas-Zambrano, Juan C., Choe, Young June
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7913196/
https://www.ncbi.nlm.nih.gov/pubmed/33540949
http://dx.doi.org/10.3390/vaccines9020117
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author Lee, Young Hwa
Harris, Rebecca C.
Oh, Hong Won
Oh, Yongho
Vargas-Zambrano, Juan C.
Choe, Young June
author_facet Lee, Young Hwa
Harris, Rebecca C.
Oh, Hong Won
Oh, Yongho
Vargas-Zambrano, Juan C.
Choe, Young June
author_sort Lee, Young Hwa
collection PubMed
description Vaccine-related errors (VREs) result from mistakes in vaccine preparation, handling, storage, or administration. We aimed to assess physicians’ and nurses’ experiences of VREs in South Korea, focusing on reconstitution issues, and to understand the barriers to and facilitators of preventing them. This was a cross-sectional study using an internet-based survey to examine experiences of reconstitution-related errors, and experience or preference with regard to ready-to-use vaccines (RTU) by physicians and nurses. A total of 700 participants, including 250 physicians and 450 nurses, responded to the questionnaire. In total, 76.4% and 41.5% of the physicians and nurses, respectively, reported an error related to reconstituted vaccines. All errors had been reported as experienced by between 4.9% and 52.0% of physicians or nurses. The errors were reported to occur in more than one in 100 vaccinations for inadequate shaking of vaccines by 28.0% of physicians and 6.9% of nurses, incomplete aspiration of reconstitution vials by 28.0% of physicians and 6.4% of nurses, and spillage or leakage during reconstitution by 20.8% of physicians and 6.9% of nurses. A total of 94.8% of physicians had experience with RTU vaccines, and all preferred RTU formulations. In conclusion, this study highlights the high frequency and types of reconstitution-related errors in South Korea. RTU vaccines could help reduce the time needed for preparation and reduce the risk of errors in South Korea.
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spelling pubmed-79131962021-02-28 Vaccine-Related Errors in Reconstitution in South Korea: A National Physicians’ and Nurses’ Survey Lee, Young Hwa Harris, Rebecca C. Oh, Hong Won Oh, Yongho Vargas-Zambrano, Juan C. Choe, Young June Vaccines (Basel) Article Vaccine-related errors (VREs) result from mistakes in vaccine preparation, handling, storage, or administration. We aimed to assess physicians’ and nurses’ experiences of VREs in South Korea, focusing on reconstitution issues, and to understand the barriers to and facilitators of preventing them. This was a cross-sectional study using an internet-based survey to examine experiences of reconstitution-related errors, and experience or preference with regard to ready-to-use vaccines (RTU) by physicians and nurses. A total of 700 participants, including 250 physicians and 450 nurses, responded to the questionnaire. In total, 76.4% and 41.5% of the physicians and nurses, respectively, reported an error related to reconstituted vaccines. All errors had been reported as experienced by between 4.9% and 52.0% of physicians or nurses. The errors were reported to occur in more than one in 100 vaccinations for inadequate shaking of vaccines by 28.0% of physicians and 6.9% of nurses, incomplete aspiration of reconstitution vials by 28.0% of physicians and 6.4% of nurses, and spillage or leakage during reconstitution by 20.8% of physicians and 6.9% of nurses. A total of 94.8% of physicians had experience with RTU vaccines, and all preferred RTU formulations. In conclusion, this study highlights the high frequency and types of reconstitution-related errors in South Korea. RTU vaccines could help reduce the time needed for preparation and reduce the risk of errors in South Korea. MDPI 2021-02-02 /pmc/articles/PMC7913196/ /pubmed/33540949 http://dx.doi.org/10.3390/vaccines9020117 Text en © 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Lee, Young Hwa
Harris, Rebecca C.
Oh, Hong Won
Oh, Yongho
Vargas-Zambrano, Juan C.
Choe, Young June
Vaccine-Related Errors in Reconstitution in South Korea: A National Physicians’ and Nurses’ Survey
title Vaccine-Related Errors in Reconstitution in South Korea: A National Physicians’ and Nurses’ Survey
title_full Vaccine-Related Errors in Reconstitution in South Korea: A National Physicians’ and Nurses’ Survey
title_fullStr Vaccine-Related Errors in Reconstitution in South Korea: A National Physicians’ and Nurses’ Survey
title_full_unstemmed Vaccine-Related Errors in Reconstitution in South Korea: A National Physicians’ and Nurses’ Survey
title_short Vaccine-Related Errors in Reconstitution in South Korea: A National Physicians’ and Nurses’ Survey
title_sort vaccine-related errors in reconstitution in south korea: a national physicians’ and nurses’ survey
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7913196/
https://www.ncbi.nlm.nih.gov/pubmed/33540949
http://dx.doi.org/10.3390/vaccines9020117
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