Cargando…

A Physiologically-Based Pharmacokinetic Framework for Prediction of Drug Exposure in Malnourished Children

Malnutrition in children is a global health problem, particularly in developing countries. The effects of an insufficient supply of nutrients on body composition and physiological functions may have implications for drug disposition and ultimately affect the clinical outcome in this vulnerable popul...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sjögren, Erik, Tarning, Joel, Barnes, Karen I., Jonsson, E. Niclas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7913226/ https://www.ncbi.nlm.nih.gov/pubmed/33540928 http://dx.doi.org/10.3390/pharmaceutics13020204

Ejemplares similares

Response to “Lactation Status and Studies of Pyrimethamine Pharmacokinetics in Pregnancy”
por: de Kock, Miné, et al.
Publicado: (2017)

Impact of malnourishment on the pharmacokinetics of acetaminophen and susceptibility to acetaminophen hepatotoxicity
por: Zillen, Daan, et al.
Publicado: (2021)

Physiologically Based Pharmacokinetic Modeling Framework for Quantitative Prediction of an Herb–Drug Interaction
por: Brantley, S J, et al.
Publicado: (2014)

Myocardial dysfunction in malnourished children
por: Faddan, Nagla Hassan Abu, et al.
Publicado: (2010)

The Future of Physiologically Based Pharmacokinetic Modeling to Predict Drug Exposure in Pregnant Women
por: Vinks, A A
Publicado: (2013)

Does the choice of applied physiologically‐based pharmacokinetics platform matter? A case study on simvastatin disposition and drug–drug interaction
por: Prieto Garcia, Luna, et al.
Publicado: (2022)

Evaluation of pharmacokinetics of single-dose chloroquine in malnourished children with malaria- a comparative study with normally nourished children
por: Kadam, Prashant P., et al.
Publicado: (2016)

Predictive Performance of Physiologically Based Pharmacokinetic and Population Pharmacokinetic Modeling of Renally Cleared Drugs in Children
por: Zhou, W, et al.
Publicado: (2016)

Pathophysiological changes that affect drug disposition in protein-energy malnourished children
por: Oshikoya, Kazeem A, et al.
Publicado: (2009)

Population Pharmacokinetic Properties of Antituberculosis Drugs in Vietnamese Children with Tuberculous Meningitis
por: Panjasawatwong, Navarat, et al.
Publicado: (2020)

A best practice framework for applying physiologically‐based pharmacokinetic modeling to pediatric drug development
por: Johnson, Trevor N., et al.
Publicado: (2021)

Gut Microbiota of Healthy and Malnourished Children in Bangladesh
por: Monira, Shirajum, et al.
Publicado: (2011)

Helicobacter pylori Infection in Malnourished Children in Lagos
por: Adeniyi, Oluwafunmilayo Funke, et al.
Publicado: (2019)

Application of Physiologically Based Pharmacokinetic Modeling to Predict Maternal Pharmacokinetics and Fetal Exposure to Oxcarbazepine
por: He, Lixia, et al.
Publicado: (2022)

Persistent Gut Microbiota Immaturity in Malnourished Bangladeshi Children
por: Subramanian, Sathish, et al.
Publicado: (2014)

Application of Physiologically Based Pharmacokinetic Modeling to Predict Acetaminophen Metabolism and Pharmacokinetics in Children
por: Jiang, X-L, et al.
Publicado: (2013)

Population Pharmacokinetic Properties of Sulfadoxine and Pyrimethamine: a Pooled Analysis To Inform Optimal Dosing in African Children with Uncomplicated Malaria
por: de Kock, Miné, et al.
Publicado: (2018)

Enantiospecific pharmacokinetics and drug–drug interactions of primaquine and blood-stage antimalarial drugs
por: Chairat, Kalayanee, et al.
Publicado: (2018)

Hypophosphataemia among Severely-malnourished Children: Case Series
por: Yoshimatsu, Shoji, et al.
Publicado: (2012)

Drug development for the treatment of onchocerciasis: Population pharmacokinetic and adverse events modeling of emodepside
por: Assmus, Frauke, et al.
Publicado: (2022)

Physiologically based pharmacokinetic modeling for predicting irinotecan exposure in human body
por: Fan, Yingfang, et al.
Publicado: (2017)

Physiologically‐Based Pharmacokinetic Modeling for Predicting Drug Interactions of a Combination of Olanzapine and Samidorphan
por: Sun, Lei, et al.
Publicado: (2020)

Primaquine Pharmacokinetics in Lactating Women and Breastfed Infant Exposures
por: Gilder, Mary Ellen, et al.
Publicado: (2018)

Bioactive glycans in a microbiome-directed food for malnourished children
por: Hibberd, Matthew C., et al.
Publicado: (2023)

Development and Evaluation of Physiologically Based Pharmacokinetic Drug–Disease Models for Predicting Rifampicin Exposure in Tuberculosis and Cirrhosis Populations
por: Rasool, Muhammad F., et al.
Publicado: (2019)

Population pharmacokinetic analysis of rivaroxaban in children and comparison to prospective physiologically‐based pharmacokinetic predictions
por: Willmann, Stefan, et al.
Publicado: (2021)

Physiologically Based Modelling Framework for Prediction of Pulmonary Pharmacokinetics of Antimicrobial Target Site Concentrations
por: Aulin, Linda B. S., et al.
Publicado: (2022)

Physiological Slowing and Upregulation of Inhibition in Cortex Are Correlated with Behavioral Deficits in Protein Malnourished Rats
por: Chaudhary, Rahul, et al.
Publicado: (2013)

Semi-physiological Enriched Population Pharmacokinetic Modelling to Predict the Effects of Pregnancy on the Pharmacokinetics of Cytotoxic Drugs
por: Janssen, J. M., et al.
Publicado: (2023)

Prediction of pyrotinib exposure based on physiologically-based pharmacokinetic model and endogenous biomarker
por: Zhang, Miao, et al.
Publicado: (2022)

Comparison of the Use of a Physiologically Based Pharmacokinetic Model and a Classical Pharmacokinetic Model for Dioxin Exposure Assessments
por: Emond, Claude, et al.
Publicado: (2005)

Risk Factors of Mortality in Severely-malnourished Children Hospitalized with Diarrhoea
por: Roy, S.K., et al.
Publicado: (2011)

Occurrence of campylobacter species in healthy well-nourished and malnourished children
por: Fernández, Heriberto, et al.
Publicado: (2008)

Hormonal Correlates and Predictors of Nutritional Recovery in Malnourished African Children
por: Nabwera, Helen M, et al.
Publicado: (2017)

Human immunodeficiency virus status in malnourished children seen at Lagos
por: Temiye, Edamisan Olusoji, et al.
Publicado: (2018)

Determinants of Mortality Among Severely Malnourished Children in Northern Nigeria
por: Nass, Shafique Sani, et al.
Publicado: (2021)

Characterizing Pharmacokinetics in Children With Obesity—Physiological, Drug, Patient, and Methodological Considerations
por: Gerhart, Jacqueline G., et al.
Publicado: (2022)

Physiologically Based Pharmacokinetic Models in the Prediction of Oral Drug Exposure Over the Entire Pediatric Age Range—Sotalol as a Model Drug
por: Khalil, Feras, et al.
Publicado: (2014)

Physiologically-Based Pharmacokinetic Modelling to Predict the Pharmacokinetics and Pharmacodynamics of Linezolid in Adults and Children with Tuberculous Meningitis
por: Litjens, Carlijn H. C., et al.
Publicado: (2023)

Physiologically Based Pharmacokinetic Modelling to Predict Imatinib Exposures in Cancer Patients with Renal Dysfunction: A Case Study
por: Rowland Yeo, Karen, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_sm8f2em8f6us6amj1qk0b8h78q