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Dapagliflozin attenuates hypoxia/reoxygenation-caused cardiac dysfunction and oxidative damage through modulation of AMPK

BACKGROUND: Emerging evidence demonstrated dapagliflozin (DAPA), a sodium-glucose cotransporter 2 inhibitor, prevented various cardiovascular events. However, the detailed mechanisms underlying its cardioprotective properties remained largely unknown. RESULTS: In the present study, we sought to inve...

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Detalles Bibliográficos
Autores principales:	Tsai, Kun-Ling, Hsieh, Pei-Ling, Chou, Wan-Ching, Cheng, Hui-Ching, Huang, Yu-Ting, Chan, Shih-Hung
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7913252/ https://www.ncbi.nlm.nih.gov/pubmed/33637129 http://dx.doi.org/10.1186/s13578-021-00547-y

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