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Mesenchymal stem cell exosome-derived miR-223 alleviates acute graft-versus-host disease via reducing the migration of donor T cells

BACKGROUND: Mesenchymal stem cells (MSCs) have been utilized in treating acute graft-versus-host disease (aGvHD) as they show strong immunosuppressive capacity through the release of various mediators, including immunosuppressive molecules, growth factors, chemokines, and exosomes. MicroRNAs (miRNAs...

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Detalles Bibliográficos
Autores principales: Liu, Weijiang, Zhou, Na, Liu, Yuanlin, Zhang, Wei, Li, Xue, Wang, Yang, Zheng, Rongxiu, Zhang, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7913292/
https://www.ncbi.nlm.nih.gov/pubmed/33637123
http://dx.doi.org/10.1186/s13287-021-02159-2