mTOR-dependent dysregulation of autophagy contributes to the retinal ganglion cell loss in streptozotocin-induced diabetic retinopathy

BACKGROUND: Neurodegeneration, an early event in the pathogenesis of diabetic retinopathy (DR), precedes clinically detectable microvascular damage. Autophagy dysregulation is considered a potential cause of neuronal cell loss, however underlying mechanisms remain unclear. The mechanistic target of...

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Detalles Bibliográficos
Autores principales: Madrakhimov, Sanjar Batirovich, Yang, Jin Young, Kim, Jin Ha, Han, Jung Woo, Park, Tae Kwann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7913405/
https://www.ncbi.nlm.nih.gov/pubmed/33637094
http://dx.doi.org/10.1186/s12964-020-00698-4

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