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Elucidating the cellular mechanism for E2-induced dermal fibrosis

BACKGROUND: Both TGFβ and estradiol (E2), a form of estrogen, are pro-fibrotic in the skin. In the connective tissue disease, systemic sclerosis (SSc), both TGFβ and E2 are likely pathogenic. Yet the regulation of TGFβ in E2-induced dermal fibrosis remains ill-defined. Elucidating those regulatory m...

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Detalles Bibliográficos
Autores principales:	Baker Frost, DeAnna, Savchenko, Alisa, Ogunleye, Adeyemi, Armstrong, Milton, Feghali-Bostwick, Carol
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7913437/ https://www.ncbi.nlm.nih.gov/pubmed/33640015 http://dx.doi.org/10.1186/s13075-021-02441-x

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