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Polymer Pro-Drug Nanoparticles for Sustained Release of Cytotoxic Drugs Evaluated in Patient-Derived Glioblastoma Cell Lines and In Situ Gelling Formulations

Glioblastoma (GBM) is the most common, malignant and aggressive brain tumour in adults. Despite the use of multimodal treatments, involving surgery, followed by concomitant radiotherapy and chemotherapy, the median survival for patients remains less than 15 months from diagnosis. Low penetration of...

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Detalles Bibliográficos
Autores principales:	Vasey, Catherine E., Cavanagh, Robert J., Taresco, Vincenzo, Moloney, Cara, Smith, Stuart, Rahman, Ruman, Alexander, Cameron
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7913572/ https://www.ncbi.nlm.nih.gov/pubmed/33546301 http://dx.doi.org/10.3390/pharmaceutics13020208

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