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Disruption of the Complex between GAPDH and Hsp70 Sensitizes C6 Glioblastoma Cells to Hypoxic Stress

Hypoxia, which commonly accompanies tumor growth, depending on its strength may cause the enhancement of tumorigenicity of cancer cells or their death. One of the proteins targeted by hypoxia is glyceraldehyde-3-phosphate dehydrogenase (GAPDH), and we demonstrated here that hypoxia mimicked by treat...

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Detalles Bibliográficos
Autores principales:	Mikeladze, Marina A., Dutysheva, Elizaveta A., Kartsev, Victor G., Margulis, Boris A., Guzhova, Irina V., Lazarev, Vladimir F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7913589/ https://www.ncbi.nlm.nih.gov/pubmed/33546324 http://dx.doi.org/10.3390/ijms22041520

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