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Repression of a large number of genes requires interplay between homologous recombination and HIRA

During homologous recombination, Dbl2 protein is required for localisation of Fbh1, an F-box helicase that efficiently dismantles Rad51–DNA filaments. RNA-seq analysis of dbl2Δ transcriptome showed that the dbl2 deletion results in upregulation of more than 500 loci in Schizosaccharomyces pombe. Com...

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Detalles Bibliográficos
Autores principales:	Misova, Ivana, Pitelova, Alexandra, Budis, Jaroslav, Gazdarica, Juraj, Sedlackova, Tatiana, Jordakova, Anna, Benko, Zsigmond, Smondrkova, Maria, Mayerova, Nina, Pichlerova, Karoline, Strieskova, Lucia, Prevorovsky, Martin, Gregan, Juraj, Cipak, Lubos, Szemes, Tomas, Polakova, Silvia Bagelova
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2021
Materias:	Gene regulation, Chromatin and Epigenetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7913671/ https://www.ncbi.nlm.nih.gov/pubmed/33511417 http://dx.doi.org/10.1093/nar/gkab027

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