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Prolactin Rescues Immature B Cells from Apoptosis-Induced BCR-Aggregation through STAT3, Bcl2a1a, Bcl2l2, and Birc5 in Lupus-Prone MRL/lpr Mice
Self-reactive immature B cells are eliminated through apoptosis by tolerance mechanisms, failing to eliminate these cells results in autoimmune diseases. Prolactin is known to rescue immature B cells from B cell receptor engagement-induced apoptosis in lupus-prone mice. The objective of this study w...
Autores principales: | Flores-Fernández, Rocio, Aponte-López, Angélica, Suárez-Arriaga, Mayra C., Gorocica-Rosete, Patricia, Pizaña-Venegas, Alberto, Chávez-Sanchéz, Luis, Blanco-Favela, Francico, Fuentes-Pananá, Ezequiel M., Chávez-Rueda, Adriana K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7913714/ https://www.ncbi.nlm.nih.gov/pubmed/33557010 http://dx.doi.org/10.3390/cells10020316 |
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