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Structural determinants of the IRF4/DNA homodimeric complex

Interferon regulatory factor 4 (IRF4) is a key transcription factor (TF) in the regulation of immune cells, including B and T cells. It acts by binding DNA as both a homodimer and, in conjunction with other TFs, as a heterodimer. The choice of homo and heterodimeric/ DNA interactions is a critical a...

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Detalles Bibliográficos
Autores principales:	Sundararaj, Srinivasan, Seneviratne, Sandali, Williams, Simon J, Enders, Anselm, Casarotto, Marco G
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2021
Materias:	Structural Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7913761/ https://www.ncbi.nlm.nih.gov/pubmed/33533913 http://dx.doi.org/10.1093/nar/gkaa1287

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