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Utilizing Dynamic Contrast-Enhanced Magnetic Resonance Imaging (DCE-MRI) to Analyze Interstitial Fluid Flow and Transport in Glioblastoma and the Surrounding Parenchyma in Human Patients

Background: Glioblastoma (GBM) is the deadliest and most common brain tumor in adults, with poor survival and response to aggressive therapy. Limited access of drugs to tumor cells is one reason for such grim clinical outcomes. A driving force for therapeutic delivery is interstitial fluid flow (IFF...

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Detalles Bibliográficos
Autores principales: Chatterjee, Krishnashis, Atay, Naciye, Abler, Daniel, Bhargava, Saloni, Sahoo, Prativa, Rockne, Russell C., Munson, Jennifer M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7913790/
https://www.ncbi.nlm.nih.gov/pubmed/33557069
http://dx.doi.org/10.3390/pharmaceutics13020212