Cargando…

Integrative Genomic–Epigenomic Analysis of Clozapine-Treated Patients with Refractory Psychosis

Clozapine (CLZ) is the only antipsychotic drug that has been proven to be effective in patients with refractory psychosis, but it has also been proposed as an effective mood stabilizer; however, the complex mechanisms of action of CLZ are not yet fully known. To find predictors of CLZ-associated phe...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mayén-Lobo, Yerye Gibrán, Martínez-Magaña, José Jaime, Pérez-Aldana, Blanca Estela, Ortega-Vázquez, Alberto, Genis-Mendoza, Alma Delia, Dávila-Ortiz de Montellano, David José, Soto-Reyes, Ernesto, Nicolini, Humberto, López-López, Marisol, Monroy-Jaramillo, Nancy
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7913835/ https://www.ncbi.nlm.nih.gov/pubmed/33557049 http://dx.doi.org/10.3390/ph14020118

Ejemplares similares

Clozapine Long-Term Treatment Might Reduce Epigenetic Age Through Hypomethylation of Longevity Regulatory Pathways Genes
por: Pérez-Aldana, Blanca Estela, et al.
Publicado: (2022)

Influence of glutathione-related genetic variants on the oxidative stress profile of Mexican patients with psychotic disorders
por: Mayén-Lobo, Yerye G., et al.
Publicado: (2023)

Relationship between APOE, PER2, PER3 and OX2R Genetic Variants and Neuropsychiatric Symptoms in Patients with Alzheimer’s Disease
por: Lozano-Tovar, Susana, et al.
Publicado: (2023)

STRA6 Polymorphisms Are Associated With EGFR Mutations in Locally-Advanced and Metastatic Non-Small Cell Lung Cancer Patients
por: Muñiz-Hernández, Saé, et al.
Publicado: (2020)

The Role of the Microbiome in First Episode of Psychosis
por: Nuncio-Mora, Lucero, et al.
Publicado: (2023)

Genome-wide association study of suicide attempt in a Mexican population: a study protocol
por: González-Castro, Thelma Beatriz, et al.
Publicado: (2019)

Gene‐level genome‐wide association analysis of suicide attempt, a preliminary study in a psychiatric Mexican population
por: González‐Castro, Thelma Beatriz, et al.
Publicado: (2019)

Mental Health Problems Due to Social Isolation During the COVID-19 Pandemic in a Mexican Population
por: Genis-Mendoza, Alma Delia, et al.
Publicado: (2021)

Knowledge, Emotions and Stressors in Front-Line Healthcare Workers during the COVID-19 Outbreak in Mexico
por: Hernández-Díaz, Yazmín, et al.
Publicado: (2021)

The Prevalence of Symptomatology and Risk Factors in Mental Health in Mexico: The 2016–17 ENCODAT Cohort
por: Medina-Mora, María Elena, et al.
Publicado: (2023)

Psychiatric Comorbidity in Mexican Adolescents with a Diagnosis of Eating Disorders Its Relationship with the Body Mass Index
por: Ruiz-Ramos, David, et al.
Publicado: (2021)

Genetic association analysis of 5‐HTR2A gene variants in eating disorders in a Mexican population
por: Genis‐Mendoza, Alma Delia, et al.
Publicado: (2019)

Variation in Actionable Pharmacogenetic Markers in Natives and Mestizos From Mexico
por: Gonzalez-Covarrubias, Vanessa, et al.
Publicado: (2019)

Individuals Diagnosed with Binge-Eating Disorder Have DNA Hypomethylated Sites in Genes of the Metabolic System: A Pilot Study
por: Rodríguez-López, Mariana Lizbeth, et al.
Publicado: (2021)

Cannabis Use in People With Obsessive-Compulsive Symptomatology: Results From a Mexican Epidemiological Sample
por: Nicolini, Humberto, et al.
Publicado: (2021)

Association between obesity and the brain-derived neurotrophic factor gene polymorphism Val66Met in individuals with bipolar disorder in Mexican population
por: Morales-Marín, Mirna Edith, et al.
Publicado: (2016)

Differential effects on neurodevelopment of FTO variants in obesity and bipolar disorder suggested by in silico prediction of functional impact: An analysis in Mexican population
por: Saucedo‐Uribe, Erasmo, et al.
Publicado: (2019)

Association of FAAH p.Pro129Thr and COMT p.Ala72Ser with schizophrenia and comorbid substance use through next-generation sequencing: an exploratory analysis
por: Martínez-Magaña, José J., et al.
Publicado: (2021)

Association and Genetic Expression between Genes Involved in HPA Axis and Suicide Behavior: A Systematic Review
por: Hernández-Díaz, Yazmín, et al.
Publicado: (2021)

Gender Differences in Suicide and Homicide Rates in Mexico City during 2019
por: Nicolini, Humberto, et al.
Publicado: (2022)

CRISPR/Cas9 genome editing approaches for psychiatric research
por: Gutiérrez-Rodríguez, Araceli, et al.
Publicado: (2023)

Clozapine for mitochondrial psychosis()
por: Finsterer, Josef, et al.
Publicado: (2017)

Effect on the expression of drd2 and drd3 after neonatal lesion in the lymphocytes, nucleus accumbens, hippocampus and prefrontal cortex: comparative analysis between juvenile and adult Wistar rats
por: Genis-Mendoza, Alma Delia, et al.
Publicado: (2016)

Gene Expression Analysis in Postmortem Brains from Individuals Who Died by Suicide: A Systematic Review
por: González-Castro, Thelma Beatriz, et al.
Publicado: (2023)

Association Study among Comethylation Modules, Genetic Polymorphisms and Clinical Features in Mexican Teenagers with Eating Disorders: Preliminary Results
por: Nolasco-Rosales, Germán Alberto, et al.
Publicado: (2021)

M93. BRAIN GENE EXPRESSION PROFILING OF INDIVIDUALS WITH DUAL DIAGNOSIS WHO DIED BY SUICIDE
por: Cabrera, Brenda, et al.
Publicado: (2020)

The Identification of Admixture Patterns Could Refine Pharmacogenetic Counseling: Analysis of a Population-Based Sample in Mexico
por: Martínez-Magaña, José Jaime, et al.
Publicado: (2020)

An international clozapine titration guideline for clozapine: An opportunity for moving forward on personalizing clozapine treatment in India and other countries
por: de Leon, Jose
Publicado: (2022)

Association between APOE polymorphisms and lipid profile in Mexican Amerindian population
por: Martínez‐Magaña, José J., et al.
Publicado: (2019)

Association between mitochondrial DNA and cognitive impairment in schizophrenia: study protocol for a Mexican population
por: García-de la Cruz, Dulce Dajheanne, et al.
Publicado: (2019)

Aggression against Nursing Personnel during the First Wave of COVID-19 Pandemic: An Internet-Based Survey
por: la Cruz, Juan Pablo Sánchez-de, et al.
Publicado: (2023)

Mental Health Impact of the COVID-19 Pandemic on Mexican Population: A Systematic Review
por: Hernández-Díaz, Yazmín, et al.
Publicado: (2022)

Association between TPH1 polymorphisms and the risk of suicide behavior: An updated meta-analysis of 18,398 individuals
por: Genis-Mendoza, Alma Delia, et al.
Publicado: (2022)

Aftereffects in Epigenetic Age Related to Cognitive Decline and Inflammatory Markers in Healthcare Personnel with Post-COVID-19: A Cross-Sectional Study
por: Nolasco-Rosales, Germán Alberto, et al.
Publicado: (2023)

Telomere Shortening in Three Diabetes Mellitus Types in a Mexican Sample
por: Cuevas Diaz, Pavel, et al.
Publicado: (2023)

Association between BDNF Val66Met polymorphism and generalized anxiety disorder and clinical characteristics in a Mexican population: A case–control study
por: González-Castro, Thelma Beatriz, et al.
Publicado: (2019)

Increased Levels of Cortisol in Individuals With Suicide Attempt and Its Relation With the Number of Suicide Attempts and Depression
por: Genis-Mendoza, Alma Delia, et al.
Publicado: (2022)

Clozapine and urinary incontinence
por: Osca Oliver, A., et al.
Publicado: (2022)

Weak Hand Grip Strength Is Associated with Alexithymia in Outpatients in a Mexican Population
por: Genis-Mendoza, Alma Delia, et al.
Publicado: (2022)

Authors' reply — Clozapine for mitochondrial psychosis
por: Demily, Caroline, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_ld1228hqeb37s6s5a2gj9pp7mu