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Leishmanicidal Activity of Betulin Derivatives in Leishmania amazonensis; Effect on Plasma and Mitochondrial Membrane Potential, and Macrophage Nitric Oxide and Superoxide Production

Herein, we evaluated in vitro the anti-leishmanial activity of betulin derivatives in Venezuelan isolates of Leishmania amazonensis, isolated from patients with therapeutic failure. Methods: We analyzed promastigote in vitro susceptibility as well as the cytotoxicity and selectivity of the evaluated...

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Detalles Bibliográficos
Autores principales:	Alcazar, Wilmer, Alakurtti, Sami, Padrón-Nieves, Maritza, Tuononen, Maija Liisa, Rodríguez, Noris, Yli-Kauhaluoma, Jari, Ponte-Sucre, Alicia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7913927/ https://www.ncbi.nlm.nih.gov/pubmed/33557150 http://dx.doi.org/10.3390/microorganisms9020320

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