Molecular Epidemiology of Group A Streptococcus Infections in The Gambia

Molecular epidemiological data on Group A Streptococcus (GAS) infection in Africa is scarce. We characterized the emm-types and emm-clusters of 433 stored clinical GAS isolates from The Gambia collected between 2004 and 2018. To reduce the potential for strain mistyping, we used a newly published pr...

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Detalles Bibliográficos
Autores principales: Jabang, Sona, Erhart, Annette, Darboe, Saffiatou, Baldeh, Aru-Kumba, Delforge, Valerie, Watson, Gabriella, Foster-Nyarko, Ebenezer, Salaudeen, Rasheed, Lawal, Bolarinde, Mackenzie, Grant, Botteaux, Anne, Antonio, Martin, Smeesters, Pierre R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7913941/
https://www.ncbi.nlm.nih.gov/pubmed/33557233
http://dx.doi.org/10.3390/vaccines9020124
Descripción
Sumario:Molecular epidemiological data on Group A Streptococcus (GAS) infection in Africa is scarce. We characterized the emm-types and emm-clusters of 433 stored clinical GAS isolates from The Gambia collected between 2004 and 2018. To reduce the potential for strain mistyping, we used a newly published primer for emm-typing. There was considerable strain diversity, highlighting the need for vaccine development offering broad strain protection.

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