Coincidence of Large Adrenal Cyst and Prominent Hyporeninemic Hyperaldosteronism

A 67-year-old Japanese woman who had end-stage renal disease was referred to our hospital for kidney transplantation. Abdominal CT revealed a large adrenal mass with inhomogeneity. She had a history of hospitalization for stroke and heart failure and exhibited prominent hyporeninemic hyperaldosteron...

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Detalles Bibliográficos
Autores principales: Sakaue, Takaaki, Okuno, Yosuke, Mukai, Kosuke, Fujita, Shingo, Kozawa, Junji, Nishizawa, Hitoshi, Matsuoka, Taka-Aki, Iwahashi, Hiromi, Norikazu, Maeda, Yamazaki, Yuto, Sasano, Hironobu, Otsuki, Michio, Shimomura, Iichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7914103/
https://www.ncbi.nlm.nih.gov/pubmed/33688442
http://dx.doi.org/10.1155/2021/8860498
Descripción
Sumario:A 67-year-old Japanese woman who had end-stage renal disease was referred to our hospital for kidney transplantation. Abdominal CT revealed a large adrenal mass with inhomogeneity. She had a history of hospitalization for stroke and heart failure and exhibited prominent hyporeninemic hyperaldosteronism. Histological examination of the resected tumor with anti-CYP11B2 antibody indicated that she had a vascular endothelial cyst with primary aldosteronism (PA) due to multiple adrenocortical micronodules. This report implicates the pathological interaction between adrenal vascular cysts and PA-mediated vascular damage of the adrenal vein.

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