Ginkgolic acid and anacardic acid are specific covalent inhibitors of SARS-CoV-2 cysteine proteases

BACKGROUND: In the urgent campaign to develop therapeutics against SARS-CoV-2, natural products have been an important source of new lead compounds. RESULTS: We herein identified two natural products, ginkgolic acid and anacardic acid, as inhibitors using a high-throughput screen targeting the SARS-...

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Detalles Bibliográficos
Autores principales: Chen, Zinuo, Cui, Qinghua, Cooper, Laura, Zhang, Pin, Lee, Hyun, Chen, Zhaoyu, Wang, Yanyan, Liu, Xiaoyun, Rong, Lijun, Du, Ruikun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7914117/
https://www.ncbi.nlm.nih.gov/pubmed/33640032
http://dx.doi.org/10.1186/s13578-021-00564-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7914117/
https://www.ncbi.nlm.nih.gov/pubmed/33640032
http://dx.doi.org/10.1186/s13578-021-00564-x

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