Mucoricin is a Ricin-Like Toxin that is Critical for the Pathogenesis of Mucormycosis

Fungi of the order Mucorales cause mucormycosis, a lethal infection with an incompletely understood pathogenesis. We now demonstrate that Mucorales fungi produce a toxin that plays a central role in virulence. Polyclonal antibodies against this toxin inhibit its ability to damage human cells in vitr...

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Detalles Bibliográficos
Autores principales: Soliman, Sameh S. M., Baldin, Clara, Gu, Yiyou, Singh, Shakti, Gebremariam, Teclegiorgis, Swidergall, Marc, Alqarihi, Abdullah, Youssef, Eman G., Alkhazraji, Sondus, Pikoulas, Antonis, Perske, Christina, Venkataramani, Vivek, Rich, Abigail, Bruno, Vincent M., Hotopp, Julie Dunning, Mantis, Nicolas J., Edwards, John E., Filler, Scott G., Chamilos, Georgios, Vitetta, Ellen S., Ibrahim, Ashraf S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7914224/
https://www.ncbi.nlm.nih.gov/pubmed/33462434
http://dx.doi.org/10.1038/s41564-020-00837-0

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