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State-dependent sequential allostery exhibited by chaperonin TRiC/CCT revealed by network analysis of Cryo-EM maps

The eukaryotic chaperonin TRiC/CCT plays a major role in assisting the folding of many proteins through an ATP-driven allosteric cycle. Recent structures elucidated by cryo-electron microscopy provide a broad view of the conformations visited at various stages of the chaperonin cycle, including a se...

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Detalles Bibliográficos
Autores principales:	Zhang, Yan, Krieger, James, Mikulska-Ruminska, Karolina, Kaynak, Burak, Sorzano, Carlos Oscar S., Carazo, José-María, Xing, Jianhua, Bahar, Ivet
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7914283/ https://www.ncbi.nlm.nih.gov/pubmed/32866476 http://dx.doi.org/10.1016/j.pbiomolbio.2020.08.006

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