The short isoform of PRLR suppresses the pentose phosphate pathway and nucleotide synthesis through the NEK9-Hippo axis in pancreatic cancer

Prolactin binding to the prolactin receptor exerts pleiotropic biological effects in vertebrates. The prolactin receptor (PRLR) has multiple isoforms due to alternative splicing. The biological roles and related signaling of the long isoform (PRLR-LF) have been fully elucidated. However, little is k...

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Detalles Bibliográficos
Autores principales: Nie, Huizhen, Huang, Pei-Qi, Jiang, Shu-Heng, Yang, Qin, Hu, Li-Peng, Yang, Xiao-Mei, Li, Jun, Wang, Ya-Hui, Li, Qing, Zhang, Yi-Fan, Zhu, Lei, Zhang, Yan-Li, Yu, Yanqiu, Xiao, Gary Guishan, Sun, Yong-Wei, Ji, Jianguang, Zhang, Zhi-Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7914341/
https://www.ncbi.nlm.nih.gov/pubmed/33664869
http://dx.doi.org/10.7150/thno.51712

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